Movie guide
The Substance (2024): movie guide
The Substance (2024) is a Horror, Science Fiction running about 142 minutes. It holds a TMDB score of 7.1/10 from 6,771 votes. Notable cast includes Demi Moore, Margaret Qualley, Dennis Quaid, Edward Hamilton-Clark. Cinema Box covers trailers, cast, and details for discovery — not full streaming.
- Released: 2024-09-18
- Runtime: 142 min
- TMDB: 7.1/10
- Genres: Horror, Science Fiction
Last updated: 2026-11-11 · First listed: 2024-09-18
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What is The Substance about?
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
Cast highlights
The Substance features Demi Moore, Margaret Qualley, Dennis Quaid, Edward Hamilton-Clark, Gore Abrams, Oscar Lesage. Open the Cinema Box title page for the full cast list and character credits.
Key facts
Release date: 2024-09-18. Runtime: 142 minutes. TMDB score: 7.1/10 (6,771 votes). Genres: Horror, Science Fiction. Original language: en. Status: Released.
Discover The Substance on Cinema Box
Cinema Box is a movie and TV discovery app for Android. Use it to browse The Substance, watch official trailers when available, save titles to your list, and plan what to watch — without hosting or streaming full films.
Frequently asked questions
- What genre is The Substance?
- The Substance is listed as Horror, Science Fiction on TMDB.
- How long is The Substance?
- The Substance runs about 142 minutes.
- Who stars in The Substance?
- Cast highlights include Demi Moore, Margaret Qualley, Dennis Quaid, Edward Hamilton-Clark, Gore Abrams, Oscar Lesage.
- Does Cinema Box stream The Substance?
- No. Cinema Box is discovery-only — trailers, details, ratings, and watchlists. It does not host or stream full movies.
- Where can I track The Substance?
- Open the The Substance page on cinemabox.app or install the official Cinema Box Android app from Google Play for watchlists and discovery tools.
